Evaluating the scope and impact of pre-diagnostic manipulative therapy in children and adolescents with osteosarcoma: A retrospective study in Uganda.

ABSTRACT:

Background

Pre-diagnosis manipulative therapies in patients diagnosed with osteosarcoma can compromise patients' outcomes. Limited literature exists on the pre-diagnosis non-oncological management of osteosarcoma, especially in resource-limited settings. We described and characterized the practice of pre-diagnosis manipulative therapy at the reference cancer treatment center in Uganda as a first step to improving the quality along the osteosarcoma treatment pathway.

Methods

We reviewed the demographic and clinical characteristics, pre-referral management, and outcome of children under 18 years treated for osteosarcoma at the Uganda Cancer Institute between January 2016 and December 2020. Data on pre-diagnosis management were extracted, as well as clinical and disease charact

SUBMITTER: Nyeko R 

PROVIDER: S-EPMC12321128 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature