Characteristics and innovative points of clinical trials of radiotherapy combined with immune checkpoint inhibitors in NSCLC over the past decade.

ABSTRACT:

Background

This study aims to statistically and qualitatively evaluate the characteristics of immunoradiotherapy (iRT) clinical trials for non-small cell lung cancer (NSCLC) registered on the ClinicalTrials.gov website over the past decade, to help researchers grasp current research trends and design higher-quality iRT clinical trials in the future.

Methods

We conducted a cross-sectional, descriptive study of interventional non-small cell lung cancer iRT clinical trials registered from 2014 to 2024. This study focuses on the combination of different radiotherapy methods with immune checkpoint inhibitors (ICIs), minimizing attention to new immunotherapeutic drugs. It emphasizes the exploration of radiotherapy and suitable patient populations. Therefore, the types of ICIs are

SUBMITTER: Li M 

PROVIDER: S-EPMC12321536 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature