Baseline terminal ileal CT and MRI measurements are associated with imaging outcomes in pediatric Crohn's disease: a cohort study.

ABSTRACT:

Background

Cross-sectional imaging is increasingly used for both initial diagnosis and long-term monitoring of Crohn's disease. The quantitative morphology of the terminal ileum may predict treatment response.

Objective

We aimed to identify baseline qualitative and quantitative imaging features that are associated with clinical and radiologic treatment response in a large cohort of children with Crohn's disease.

Materials and methods

This was a retrospective study of the RISK cohort study in pediatric Crohn's disease. This multicenter study included 1,136 children <18 years from 28 sites in North America. Subjects enrolled with newly diagnosed Crohn's disease who underwent endoscopy with baseline and follow-up CT or MRI were considered for this study. Exclusion criter

SUBMITTER: Ta AD 

PROVIDER: S-EPMC12321652 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature