Advances in grape and pathogen genomics toward durable grapevine disease resistance.

ABSTRACT: The future sustainability of viticulture depends on the development of grapevine cultivars with genetic resistance to diseases such as powdery mildew, downy mildew, and Pierce's disease. Recent advances in grape and pathogen genomics have dramatically improved our approach to durable disease resistance. The availability of diploid genome references for wild species, combined with the ability to phase resistance haplotypes and conduct genome-wide association and expression analyses, has greatly enhanced our ability to dissect genetic resistance loci. This progress is yielding candidate genes that will form the foundation for precise breeding, gene stacking, and genome editing in grape improvement programs. As resistance genes are deployed in vineyards, pathogen populations evolve to adapt a

SUBMITTER: Paineau M 

PROVIDER: S-EPMC12321742 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature