Recent progress in stem cell and immune cell-based interventions for aging and age-related disorders.

ABSTRACT: The extension of human lifespan has intensified the demand for developing more effective strategies to enhance quality of life. Age-related physiological decline and associated diseases now constitute significant societal challenges. As scientific understanding of aging mechanisms deepens, targeted intervention in the aging process is becoming increasingly feasible. Emerging evidence suggests that lifespan extension with preserved healthspan can be achieved through metabolic modulation and innovative molecular biology approaches. Notably, cell-based therapies demonstrate substantial anti-aging potential via multiple mechanisms including metabolic reprogramming, cellular repair systems, tissue regeneration, senescent cell clearance, and immunomodulation. This has catalyzed the emergence of

SUBMITTER: He L 

PROVIDER: S-EPMC12321787 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature