Does Helicobacter pylori have a role in the pathogenesis of otitis media with effusion, or is it a fallacy??

ABSTRACT:

Purpose

Helicobacter pylori, causing chronic systemic infection, may colonize in middle ear milieu and conduce to effusion collection. Many investigations on relationship between pathogenesis of otitis media with effusion (OME) and Helicobacter pylori yielded conflicting results. We investigated Helicobacter pylori presence in effusion and adenoid samples of children having OME and in middle ear and adenoid samples of children with healthy middle ears to elucidate its role on OME pathogenesis.

Methods

This prospective case-control study included 300 patients aged 1-12 years. One-hundred effusion samples collected from 100 children undergoing ventilation tube insertion and adenoidectomy due to chronic OME and adenoid hypertrophy formed study group, and 100 adenoid samples col

SUBMITTER: Gunduz AY 

PROVIDER: S-EPMC12321910 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature