Hemorrhagic transformation in acute ischemic stroke: hemorrhagic subtypes and symptomatic intracranial hemorrhage.

ABSTRACT:

Background

Few clinical studies perform detailed analyses of subtypes of intracranial hemorrhage (ICH) after mechanical thrombectomy (MT) used to treat acute ischemic stroke. Symptomatic intracranial hemorrhage (sICH) is a formidable complication of MT and is widely used in clinical trials as a safety outcome. However, variable definitions of sICH are used across clinical studies.

Objective

To radiographically subcategorize post-MT ICH development within this large cohort and examine overlap with sICH. Second, to examine the agreement of this definition of sICH with local site-reported occurrences of sICH to see how sICH rates change with modifications of the definitions used.

Methods

A large cohort of patients treated with MT for acute ischemic stroke (n=1395) was an

SUBMITTER: Luff MK 

PROVIDER: S-EPMC12322388 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature