Future risk projection to engage 'near-miss' individuals in lung cancer screening eligibility: an analysis of ILST data.

ABSTRACT:

Introduction

Lung cancer risk increases with time, and participants who are initially ineligible for lung cancer screening (LCS) could become eligible later. The aim of this study was to determine the proportion of people (initially ineligible) who may become eligible in a risk model-based LCS programme and the impact smoking cessation could have on this cohort.

Methods

All potential participants for the International Lung Screening Trial aged 55-80 years, ineligible for Low-dose CT screening at baseline (PLCO_m2012<1.5% 6-year risk), were included. Assuming annual increments of change in age, smoking duration and quit time, and under the assumption of other risk variables being constant, projections of risk were made using the PLCO_m2012 model from evalu

SUBMITTER: Kumarasamy C 

PROVIDER: S-EPMC12322426 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature