Impact of serum calcium levels on the occurrence of sepsis and prognosis in hospitalized patients with concomitant psoriasis: a retrospective study based on the MIMIC-IV database.

ABSTRACT:

Objective

This study aims to investigate the relationship between serum calcium levels during hospitalization and the incidence and prognosis of sepsis in hospitalized patients with psoriasis.

Methods

A retrospective analysis of patients with concomitant psoriasis admitted for the first time was conducted, utilizing the Medical Information Mart for Intensive Care database. Machine learning techniques, along with logistic regression, Cox regression, group-based trajectory modeling (GBTM), and mediation analysis, were employed to assess the influence of serum calcium levels and other clinical indicators on the occurrence of sepsis and all-cause mortality.

Results

Serum calcium exhibits a significant inverse correlation with the occurrence of sepsis [odds ratio (OR) =0.3

SUBMITTER: Zheng X 

PROVIDER: S-EPMC12322502 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature