Multiparametric MRI-Based Intratumoral and Peritumoral Radiomics for Distinguishing Solitary Intrahepatic Mass-Forming Cholangiocarcinoma From Colorectal Liver Metastases.

ABSTRACT:

Objective

To establish a model based on intratumoral and peritumoral radiomics for preoperatively differentiating solitary intrahepatic mass-forming cholangiocarcinoma (IMCC) lesions from colorectal cancer liver metastases (CRLM).

Methods

Preoperative MRI scans from IMCC patients were retrospectively obtained from three academic medical centers. Radiomics features were extracted from the intratumoral and multiple peritumoral regions. After feature selection, the optimal peritumoral range was determined. The radiomics model was developed by integrating both single-sequence and multisequence models through probabilistic ensemble learning. Significant variables from clinical imaging features, radiomics, were integrated into a combined model, and its performance was evaluated us

SUBMITTER: Zhuo L 

PROVIDER: S-EPMC12322924 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature