Acute Metabolic Effects in Brazilian A-29 Fighter Pilots by NMR-Based Metabolomics.

ABSTRACT: Operating an aircraft imposes significant physical and mental demands on pilots, particularly those in military aviation. These challenges include circadian disruptions, irregular working hours, and exposure to G-forces. This study investigates the acute metabolic effects of flight in the A-29 fighter pilots of the Brazilian Air Force (FAB). Blood, urine, and saliva samples were collected from 32 pilots, trainees (n = 12; aged 23-26 years) and instructors (n = 20; aged 25-41 years), immediately before and after flights. Assessments included anthropometric measurements, complete blood count (CBC), circulating endothelial cells (CECs), coagulogram, lipidogram, urinalysis, and nuclear magnetic resonance (NMR)-based metabolomics. After flights, trainees showed a 12% increase in t

SUBMITTER: Verissimo Franca de Oliveira R 

PROVIDER: S-EPMC12322951 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature