Transcriptome-Proteome Profiling in <i>Burkholderia thailandensis</i> during the Transition from Exponential to Stationary Phase.

ABSTRACT: Burkholderia thailandensis is closely related to, and a surrogate for, highly pathogenic Burkholderia species. Like other bacterial cells, it commonly exists in the stationary phase, for instance, within a host cell. Understanding the molecular mechanisms that characterize the transition from exponential to stationary phases is therefore critical to understanding responses to stress or nutrient limitation. We present here an integrated transcriptomic and proteomic analysis of mRNA and protein abundance changes during entry into the stationary phase. We identified 928 differentially accumulating mRNAs and 832 differentially accumulating proteins. mRNAs encoding proteins involved in benzoate degradation and O-antigen nucleotide sugar biosynthesis were elevated in the stationary

SUBMITTER: Al-Tohamy A 

PROVIDER: S-EPMC12322963 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature