A nomogram model for predicting maternal cardiovascular complications and neonatal adverse outcomes in pregnant patients with pulmonary arterial hypertension.

ABSTRACT:

Background

Pulmonary arterial hypertension (PAH) during pregnancy significantly increases maternal and fetal mortality risk. We developed nomogram prediction models from retrospective data to assess maternal cardiovascular risks and neonatal adverse outcomes.

Methods

Our study included 170 pregnant women, divided into training (70%) and validation (30%) sets. Predictors of outcomes were identified using logistic regression in the training set, and nomograms were constructed to predict maternal cardiovascular complications and neonatal adverse outcomes. Model performance was evaluated through internal validation.

Results

Predictors of cardiovascular complications included severe PAH (OR = 4.80), New York Heart Association (NYHA) classification ≥ III (OR = 25.94), ST-T

SUBMITTER: Ma R 

PROVIDER: S-EPMC12322992 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature