Efficacy of early rituximab treatment in anti-mGluR1 encephalitis: a case report.

ABSTRACT:

Background

Anti-mGluR1 encephalitis is a form of autoimmune encephalitis, with limited reports globally and only two cases reported from Japan. There are uncertainties regarding the optimal immunosuppressive agents and individual drug responses. Herein, we report a case of anti-mGluR1 encephalitis from Japan, notable for a favorable outcome after an early rituximab initiation and an observed increase in cerebellar blood flow during the early disease stages.

Case presentation

The patient was a 65-year-old woman who experienced dizziness for 3 months, followed by worsening gait instability. She was referred to our department due to progressive difficulty standing and walking. Neurological examination revealed dysarthria, severe cerebellar ataxia, and impaired performance on th

SUBMITTER: Yamada K 

PROVIDER: S-EPMC12323163 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature