Impact of intestinal bacteria on biofilm formation, motility, virulence, and gene expression in <i>Vibrio parahaemolyticus</i>.

ABSTRACT: Vibrio parahaemolyticus, a foodborne pathogen, is a leading cause of acute gastroenteritis in humans. In contrast, non-pathogenic Escherichia coli is a common commensal bacterium residing in the human gut. Despite their co-occurrence during infection, the interaction between these two species remains poorly understood. This study revealed that V. parahaemolyticus outcompetes E. coli under co-culture conditions, demonstrating superior growth efficiency and competitive dominance. Co-cultivation stimulated biofilm formation in both species, with E. coli culture supernatant specifically enhancing biofilm development in V. parahaemolyticus. Nevertheless, V. parahaemolyticus dominated mixed microbial colonies. Additionally, co-cultivation reduced

SUBMITTER: Huang Q 

PROVIDER: S-EPMC12323305 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature