Long-term outcomes of initial thoracic endovascular repair versus medical therapy in acute uncomplicated type B aortic dissection: real-world evidence from a nationwide claims database in Japan - a retrospective cohort study.

ABSTRACT:

Objectives

To compare the long-term outcomes of initial thoracic endovascular aortic repair (TEVAR) versus initial medical therapy (iMT) in patients with acute uncomplicated type B aortic dissection (uTBAD), using real-world evidence from a nationwide claims database in Japan. This study aligns with stage 4 of the Idea, Development, Exploration, Assessment, and Long-term Study (IDEAL) framework for surgical innovation.

Design

A retrospective cohort study using propensity score matching (PSM) to balance baseline characteristics.

Setting

Japanese nationwide health insurance claims database, between 1 January 2015 and 31 December 2023.

Participants

Among 40 229 cases with tentative codes for aortic dissection (International Classification of Diseases-10: I71.0), 4

SUBMITTER: Kimura Y 

PROVIDER: S-EPMC12323521 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature