Structural determinants of racial disparities in breast cancer survival in Alabama.

ABSTRACT: Background Despite improvements in breast cancer survival, Black versus White women remain at higher risk of death. Exploring reasons behind this disparity is necessary to facilitate interventions. This study evaluated rural-urban residence and/or area deprivation index (ADI) as mediators of the association between race and survival in adults with breast cancer in Alabama. Methods This retrospective, population-based cohort included 25,195 adult Black or White women with incident breast cancer in Alabama between 1/1/2010 and 12/31/2019. Exposure was self-reported race; mediators were rural-urban status (Rural-Urban Commuting Area codes) and neighborhood deprivation (state-level ADI). Outcome was overall survival from diagnosis to death (any cause) or end of follow-up (12/31/2021). Results

SUBMITTER: Fowler ME 

PROVIDER: S-EPMC12323589 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature