Genomic insights into clinical non-O1/non-O139 <i>Vibrio cholera</i>e isolates in Japan.

ABSTRACT: Non-O1/non-O139 Vibrio cholerae (NOVC) causes sporadic intestinal infections and systemic symptoms. Recently, global warming has led to an increase in NOVC infections; however, there have been no reports on the genomic analysis of clinical NOVC isolates in Japan, and the molecular understanding of NOVC remains inadequate. We identified three cases of NOVC infection in Nagoya, Japan, in 2020 and performed genomic analysis to reveal the molecular characteristics of these isolates and compared them with those of previously reported clinical cases. Phylogenetic analysis revealed high diversity. This result indicates that the three cases were sporadic within the area over a short period of time from multiple contaminated sources. However, most clinical isolates carried virulence factor g

SUBMITTER: Kobayashi Y 

PROVIDER: S-EPMC12323619 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature