Heterogeneity among <i>Mycobacterium avium</i> complex species isolated from pulmonary infection in Taiwan.

ABSTRACT: Mycobacterium avium complex (MAC) is an emerging pathogen causing nontuberculous pulmonary infections globally. However, clinical treatment guidelines regard MAC as a single entity, recommending a universal anti-mycobacterial combination therapy. Our study aimed to distinguish species among MAC and investigate the antimicrobial susceptibility for the selection of optimal antimicrobial agents in Taiwan. Two hundred ninety-four consecutive sputum samples confirmed as MAC by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were collected from 1 November 2015 to 31 August 2020 at Linkou Chang Gung Memorial Hospital in Taiwan. These isolates were identified through 16S rRNA gene, 23S rRNA gene, heat-shock protein 65 gene (hsp65), internal transcribed sp

SUBMITTER: Lin H-M 

PROVIDER: S-EPMC12323620 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature