A case of membranous nephropathy complicated by autoimmune hepatitis and primary biliary cholangitis.

ABSTRACT:

Rationale

Membranous nephropathy (MN) is an important and common cause of nephrotic syndrome in adults. Overlap syndrome is an infrequent clinical subgroup characterized by the coexistence of autoimmune hepatitis, primary biliary cholangitis or primary sclerosing cholangitis. Coexistence of MN and autoimmune liver diseases is rare. Several reports have documented the concurrent presence of multiple autoimmune diseases, suggesting a potential mechanism linking these disorders.

Patients concerns

A 53-year-old male patient diagnosed with phospholipase A2 receptor-related MN accompanied by recurrent increases in aminotransferases during treatment.

Diagnoses

The patient was finally diagnosed as MN with primary biliary cholangitis-autoimmune hepatitis overlap syndrome based

SUBMITTER: Lei X 

PROVIDER: S-EPMC12323911 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature