Disentangling multivariate relationships between cognition, language and social traits: structures of G, E, and r G E .

ABSTRACT:

Background

Cognitive, language, and social abilities are complex, heritable and intertwined traits shaping children's development and later mental health. To better understand cross-trait interrelationships, we model here the structures of shared genomic and shared non-genomic/residual (i.e. broadly environmental) influences, and their correlation ( rGE ), investigating cognitive, language, and social behavioural/communication measures.

Methods

Data were obtained for unrelated children (8-13 years) from two population-based cohorts: the UK Avon Longitudinal Study of Parents and Children (ALSPAC, N≤6,543) and the US Adolescent Brain Cognitive Development^℠ (ABCD) Study (N≤4,412), and analyses were carried out implementing an extended data-driven genetic-relationship

SUBMITTER: Schlag F 

PROVIDER: S-EPMC12324258 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature