High Resting Heart Rate Is Associated with Cardiovascular Death in Patients with Stroke, Independent of Sex.

ABSTRACT:

Introduction

High resting heart rate (HRHR) is a surrogate marker of increased sympathetic outflow. In acute stroke patients, HRHR is more commonly observed in women than in men. We analyzed whether HRHR (>86 bpm) adds incremental prognostic value for stroke outcomes in women.

Methods

We analyzed data of 6,024 patients (2,568 women, mean age 68.98 years) with acute ischemic stroke from the Virtual International Stroke Trials Archive (VISTA).

Results

Patients with HRHR were more often female (45.3 vs. 41.8%, p = 0.017), younger (66.0 ± 13.2 vs. 67.8 ± 12.6 years, p < 0.001), had higher baseline systolic blood pressure and more often diabetes. The primary composite endpoint of recurrent ischemic stroke, transient ischemic attack, myocardial infarction, or cardiovascular

SUBMITTER: Heuer C 

PROVIDER: S-EPMC12324698 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature