Palmoplantar Pustulosis during Pregnancy Was Successfully Treated with Tofacitinib: A Case Report.

ABSTRACT:

Introduction

Palmoplantar pustulosis (PPP) is a common chronic recurrent skin disease characterized by sterile pustules on the palms and soles of the feet. Most patients with PPP have a rash that improves during pregnancy due to the influence of estrogen and progesterone, but relatively few have an exacerbation of the rash during pregnancy.

Case introduction

Here, we show a female patient diagnosed with PPP, whose rash worsened during pregnancy and gestation. Her lesions were painful and cracked, interfering with normal walking and sleep, and was poorly treated with hormonal ointments and ultraviolet light. She gave birth to a healthy baby boy at 39 weeks plus 4 days of gestation after regular monitoring and stopped breastfeeding at 6 months of age and then presented to the

SUBMITTER: Dong B 

PROVIDER: S-EPMC12324728 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature