Optimization of Silver Nanoparticle Dermal Patch Films for Enhanced Wound Healing: Formulation and Characterization Study.

ABSTRACT: Background: Silver nanoparticles (AgNPs) are known for their potent antibacterial properties, making them suitable for wound healing applications. Aims: This study focuses on formulating AgNPs into dermal patch films (DPFs), leveraging the adhesive properties of the film for the effective delivery of active ingredients. Methods: AgNPs were synthesized through a green synthesis method using Plantago major L. Leaf extract as a bioreductant. Five distinct formulations, ranging from AgNP concentration of 0% (control), 0.005%, 0.01%, 0.05%, and 0.10%, were optimized and denoted as Formulas 1-5 (F1-F5), respectively. The films were fabricated by solvent casting method employing a manual film applicator. A variety of evaluations were then performed on the films, includ

SUBMITTER: Nawatila R 

PROVIDER: S-EPMC12324911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature