Supplementation with porcine placenta extract reduces negative emotions and enhances positive emotions in healthy adults: a randomized, double-blind, placebo-controlled study.

ABSTRACT:

Background

Mental health conditions such as depression, anxiety, and stress represent significant global health challenges. According to the World Health Organization, there is an urgent need for safe and effective interventions to alleviate this burden. However, existing approaches to address these conditions remain insufficient. Placenta extract, obtained by enzymatic digestion of the placenta, has demonstrated efficacy in improving menopausal symptoms and may represent a novel interventional option.

Objective

This study aimed to evaluate the effects of porcine or equine placenta extract (pPE or ePE, respectively) intake on stress levels in healthy adults.

Methods

This was a 12-week, randomized, double-blind, placebo-controlled study (ClinicalTrials Identifier: UMIN

SUBMITTER: Morita N 

PROVIDER: S-EPMC12325048 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature