Comparative evaluation of spontaneous breathing trial techniques for ventilator weaning: a bench study.

ABSTRACT:

Background

Spontaneous breathing trials (SBT) are crucial for determining when mechanically ventilated patients are ready for extubation. While pressure support (PS) and T-piece trials are commonly used, humidified high-flow (HHF) is increasingly considered, but its physiological effects remain unclear. This bench study compares T-piece, PS, and HHF modalities, evaluating their impact on work of breathing (WOB), tidal volume (Vt), total positive end-expiratory pressure (PEEPtot) and CO₂ clearance.

Methods

A 3D-printed manikin head connected to an artificial lung was used. Four SBT modalities were tested: T-piece with and without supplemental oxygen, PS at 7 cmH₂O (PEEP 0 cmH₂O), and HHF at 50 L/min. The tests were performed under three lung c

SUBMITTER: Fossat G 

PROVIDER: S-EPMC12325126 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature