Increased intra-subject variability in reward behavior relates to symptom severity in schizophrenia.

ABSTRACT: Schizophrenia (SZ) is a complex disorder characterized by positive and negative symptoms that have been linked to dysfunction in cognition and reward motivation. Recent findings show higher inter-subject variability in SZ in various cognitive functions. This raises the question of whether there is also higher intra-subject variability in SZ at the psychological level, specifically increased variability across the trials of a psychological task within the subject itself, that is, intra-subject variability. To examine fluctuations in behavior during a reward-based discrimination and liking task, we analyzed intra-subject variability in SZ and observed the following: (i) increased intra-subjective variability across all four behavioral measures, that is, response times (RT) for discrimination

SUBMITTER: Chen IF 

PROVIDER: S-EPMC12325774 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature