Short-term repeatability and postprandial effect assessment of liver perfusion quantification in healthy subjects using arterial spin labeling MRI.

ABSTRACT:

Objectives

To assess the stability of liver perfusion quantification using arterial spin labeling MRI (ASL-MRI) in healthy subjects.

Materials and methods

The arterial and portal venous liver perfusion were measured with two pseudo-continuous ASL acquisitions at a 3.0-Tesla MRI system. To assess the short-term repeatability of ASL-MRI, twelve healthy subjects underwent three consecutive ASL examinations in the fasting state. Following meal ingestion, the postprandial liver perfusion was measured. Changes in liver perfusion measured by ASL before and after meal ingestion, and their correspondence with portal vein hemodynamic variations assessed by Doppler ultrasonography (US), were analyzed to evaluate the stability of ASL in detecting postprandial perfusion alterations.

R

SUBMITTER: Ren P 

PROVIDER: S-EPMC12325835 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature