Hemolysis, hemolytic markers, and mortality in sepsis: a scoping review.

ABSTRACT:

Background

Despite advanced and early treatment in the intensive care unit (ICU), mortality in patients with sepsis remains high. Sepsis is often associated with hemolysis. In the clinical routine, hemolysis is often overlooked, as markers of hemolysis are often not routinely measured. Aim of this scoping literature review is to quantify the incidence and extent of hemolysis in patients with sepsis and the association with mortality.

Methods

Systematic literature search in bibliographic databases MEDLINE, EMBASE and Web of Science for sepsis and hemolysis.

Results

A total of 3382 studies underwent title-abstract screening and 169 studies were reviewed in full. There were 34 studies with a total of 27,702 patients with sepsis and reported hemolysis or hemolytic markers

SUBMITTER: Bunger V 

PROVIDER: S-EPMC12325840 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature