Associations of serum carotene levels and decline for the ability of attention: a longitudinal study in the Japanese general population.

ABSTRACT:

Background

Although serum carotene may contribute to dementia prevention, there is a lack of longitudinal evidence for early cognitive decline before dementia symptoms. The aim of this study was to examine whether serum carotene levels were associated with annually evaluated cognitive trajectories among the Japanese general population.

Methods

Among 581 baseline participants, 199 individuals (83 males; mean age [min, max], 62.7 [39, 90] years) who underwent cognitive assessments more than twice after baseline were analyzed. "Attention" levels were assessed using one- and three-target Digit Cancellation Tests (D-CAT1 and D-CAT3). "General cognitive ability" was assessed by the short version of Mini-Mental State Examination (SMMSE). Serum carotenes (α-carotene, β-carotene and

SUBMITTER: Okumiyama H 

PROVIDER: S-EPMC12326196 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature