Transcriptomic and metabolomic analyses reveal molecular mechanisms of tobacco mosaic virus (TMV) resistance in Nicotiana tabacum L.

ABSTRACT: Tobacco mosaic virus (TMV) severely impairs plant growth, leading to significant economic losses in the production of various Solanaceae crops, including tobacco (Nicotiana tabacum), tomato (Solanum lycopersicum) and pepper (Caspicum annuum). To investigate TMV resistance mechanisms, we analyzed the transcriptomic and metabolomic profiles of susceptible (K326) and resistant (R_K326) tobacco lines. Transcriptomic analysis revealed that the number of differentially expressed genes (DEGs) in R_K326 was about 2 times higher than in K326 at 9 days post-inoculation (dpi), suggesting a greater involvement of defense-related genes in the resistant line. KEGG pathway analysis of DEGs highlighted the significant enrichment of biotic-stress related pathways that were specifically activated in R_K326

SUBMITTER: Li C 

PROVIDER: S-EPMC12326589 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature