Effects of photobiomodulation on multiple health outcomes: an umbrella review of randomized clinical trials.

ABSTRACT:

Background

Photobiomodulation (PBM) is a non-invasive therapy increasingly used for pain, inflammation, and tissue repair, yet a comprehensive synthesis of its effectiveness across multiple health outcomes remains lacking. Herein, we aimed to systematically assess the clinical effects and strength of evidence for PBM across a wide range of health outcomes using data from existing meta-analyses of randomized controlled trials (RCTs).

Methods

We conducted an umbrella review of meta-analyses of RCTs, searching five databases up to December 8, 2023. Two reviewers independently assessed methodological quality using AMSTAR 2 and evaluated certainty of evidence using a modified GRADE framework. Pooled effect sizes were recalculated as equivalent standardized mean differences (eSMD)

SUBMITTER: Son Y 

PROVIDER: S-EPMC12326686 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature