Preoperative MRI and CA19-9 for predicting occult lymph node metastasis in small pancreatic ductal adenocarcinoma (≤ 2 cm).

ABSTRACT:

Aim

Accurate prediction of occult lymph node metastasis (OLNM) in small pancreatic ductal adenocarcinoma (sPDAC) (≤ 2 cm) is crucial for curative management. This study aims to explore clinical and MRI features associated with OLNM in sPDAC and their pathological and prognostic implications.

Materials and methods

This retrospective study included 135 patients with pathologically confirmed sPDAC who underwent surgery between September 2014 and September 2023. Preoperative multi-sequence MRI, clinical data, and pathological features were analyzed. Univariate and multivariate logistic regression models were used to identify risk predictors of OLNM in sPDAC. Receiver operating characteristic (ROC) analysis was performed to assess diagnostic performance and Kaplan-Meier survival

SUBMITTER: Tang Q 

PROVIDER: S-EPMC12326715 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature