Global burden and trend of rheumatic heart disease among women of childbearing age, 1990-2021, with projection to 2040.

ABSTRACT:

Objectives

This study aims to assess the global burden, trends, and regional variations of rheumatic heart disease (RHD) among women of childbearing age (WCBA), contributing to better-targeted prevention and management strategies.

Methods

Data from the Global Burden of Disease Study (GBD) 2021 were analyzed to estimate the incidence, mortality, and disability-adjusted life years (DALYs) due to RHD among WCBA globally and by region from 1990 to 2021. Projections of the RHD incidence rate from 2022 to 2040 were generated using the Bayesian age-period-cohort model.

Results

In 2021, there were 1,248,510 new cases of RHD among WCBA, with an age-standardized incidence rate (ASIR) of 64.31 per 100,000 population. RHD resulted in 40,195 deaths and 3,190,496 DALYs, with age-st

SUBMITTER: Chen Y 

PROVIDER: S-EPMC12326764 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature