An olive oil-derived NAE mixture (Olaliamid^®) improves liver and cardiovascular health, and decreases meta-inflammation in naturally obese dogs: a double-blind, randomized, placebo-controlled study.

ABSTRACT:

Background

Canine obesity is a common disorder accompanied by a low-grade chronic inflammation and is considered a risk factor for liver and heart diseases. The present study aimed to investigate whether an olive oil-derivative enriched in N-acylethanolamines (Olaliamid^®, OLA) may protect dogs against obesity-induced comorbidities.

Results

Twenty-seven dogs of mixed breed and size with a body condition score ≥ 7/9 were included in the trial, once provided they were otherwise healthy. Dogs were fed a commercial maintenance diet for two weeks before enrolment, and randomized in two groups, i.e., OLA (n = 14) and placebo (OLA vehicle; n = 13). Both treatments were administered orally by the owners in a liquid form at 0.7 ml/5kg body weight, once a day for three month

SUBMITTER: Diego P 

PROVIDER: S-EPMC12326773 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature