Uncovering the link between cardiometabolic index and depression in diabetes: a large-scale population study.

ABSTRACT:

Background

Studies have shown that individuals with diabetes are more likely to suffer from depression, and metabolic dysregulation may be the pathophysiological mechanism underlying this comorbidity. The Cardiometabolic Index (CMI) is an innovative metric that integrates abdominal obesity and lipid levels, providing a comprehensive assessment of cardiometabolic health. Currently, the relationship between CMI and depression in diabetes has not been clarified. This study aims to explore the association between CMI and depression among American adults with diabetes.

Methods

This study enrolled 3,182 patients with diabetes from the National Health and Nutrition Examination Survey (2005-2018). A multivariable logistic regression model, restricted cubic spline (RCS) regression an

SUBMITTER: Ma N 

PROVIDER: S-EPMC12326782 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature