Predictive role of the geriatric nutritional risk index in all-cause and cardiovascular mortality among elderly patients with osteoarthritis.

ABSTRACT:

Objective

We intended to investigate the correlation of the geriatric nutritional risk index (GNRI) and the risks of all-cause and cardiovascular mortality in elderly patients with osteoarthritis (OA).

Methods

This study included 2,922 OA patients aged ≥ 60 years from National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018. GNRI was obtained using serum albumin and body weight, with participants stratified into high (≥ 98) and low (< 98) GNRI groups. Cox regressions, survival analysis, and restricted cubic spline (RCS) regression have been utilized to assess mortality risks. Nonlinear threshold effects were evaluated using piecewise regression. Moreover, subgroup analyses have also been completed based on demographic, lifestyle, and clinical features.

SUBMITTER: Jiang Z 

PROVIDER: S-EPMC12326807 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature