Exploring patients' experiences with wAIHA and the content validity of the FACIT-fatigue: a qualitative interview study.

ABSTRACT:

Background

Warm Autoimmune Hemolytic Anemia (wAIHA) is a rare form of anemia caused by premature destruction of red cells. This qualitative study aimed to understand the patient experience with wAIHA and provide evidence of FACIT-Fatigue scale validity by interviewing adult wAIHA patients along with examining patients' definitions of meaningful change for item 1 of the FACIT Fatigue.

Methods

Hybrid Concept Elicitation (CE) and Cognitive Debriefing (CD) interviews, lasting approximately 75 min, were conducted with US-based adults diagnosed with wAIHA. The CE part of the interview focused on understanding the patient's experiences with wAIHA, particularly the signs/symptoms, and impacts. The CD part evaluated patient's feedback on clarity, relevance, and comprehensibility of t

SUBMITTER: Shukla A 

PROVIDER: S-EPMC12326857 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature