Global trends and epidemiological shifts in gastrointestinal cancers: insights from the past four decades.

ABSTRACT:

Background

The epidemiological profiles of gastrointestinal (GI) cancers vary across countries and over time, largely reflecting variations in risk factors and screening practices. We aimed to provide an overview of the current global burden of the five major types of GI cancers and conduct an updated evaluation of the long-term trends of GI cancers.

Methods

The updated numbers of new cases and deaths, and age-standardized rates (ASR), of the five GI cancers for 185 countries were sourced from the GLOBOCAN 2022, and presented by cancer site, continent, and human development index (HDI). For 43 countries, annual incidence and mortality data were obtained from the Cancer Incidence in Five Continents Plus and World Health Organization mortality databases, supplemented by the mo

SUBMITTER: Li M 

PROVIDER: S-EPMC12328094 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature