Redox-powered autonomous directional C-C bond rotation under enzyme control.

ABSTRACT: Living biological systems rely on the continuous operation of chemical reaction networks. These networks sustain out-of-equilibrium regimes in which chemical energy is continually converted into controlled mechanical work and motion^1-3. Out-of-equilibrium reaction networks have also enabled the design and successful development of artificial autonomously operating molecular machines^4,5, in which networks comprising pairs of formally-but non-microscopically-reverse reaction pathways drive controlled motion at the molecular level. In biological systems, the concurrent operation of several reaction pathways is enabled by the chemoselectivity of enzymes and their cofactors, and nature's dissipative reaction networks involve several classes of reactions. By contrast, the r

SUBMITTER: Berreur J 

PROVIDER: S-EPMC12328200 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature