All-cause and cause-specific mortality in psoriasis patients: a systematic review and meta-analysis.

ABSTRACT:

Objective

The objective of this meta-analysis is to assess the all-cause and cause-specific mortality in patients with psoriasis.

Method

In accordance with PRISMA guidelines, a systematic search of PubMed, EMBASE, and the Cochrane Library (from inception to March 2025) was conducted. Eligible studies comprised English-language cohort studies comparing mortality risk (HR/OR/RR) in adults with psoriasis versus healthy/non-psoriasis controls. Two reviewers independently screened studies, extracted data, and assessed study quality using the Newcastle-Ottawa Scale. Hazard ratios (HRs) were synthesized using random-effects models in Stata 14.0. Sensitivity analyses, subgroup analyses, and assessments of publication bias (via funnel plots and Egger's test) were also performed.

R

SUBMITTER: Yang Y 

PROVIDER: S-EPMC12328333 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature