Prognostic stratification in myocardial infarction using the modified CONUT score: a multidimensional biomarker from the MIMIC-IV cohort.

ABSTRACT:

Background

Malnutrition is increasingly recognized as a modifiable prognostic factor in myocardial infarction (MI), yet traditional nutritional assessment methods often fail to adequately capture lipid-related atherogenic risk. We introduced an innovative modified Controlling Nutritional Status (mCONUT) score, which replaces total cholesterol with non-HDL cholesterol, aiming to improve the stratification of atherosclerotic risk and to assess its prognostic utility in predicting MI outcomes.

Methods

In this retrospective cohort study, we analyzed a total of 3,730 patients diagnosed with MI, extracted from the MIMIC-IV database, and stratified them into Normal, Mild, and Worse groups based on the mCONUT score. After performing 1:1:1 propensity score matching, we selected 993 p

SUBMITTER: Yu W 

PROVIDER: S-EPMC12328424 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature