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Evaluation of different sedation scales in the ICU management of COVID-19 patients.


ABSTRACT: This study evaluated the inter-rater reliability and diagnostic validity of different sedation scales for COVID-19 patients in the ICU, focusing on optimizing patient management and outcomes amidst unique pathophysiological challenges. Seventy-three mechanically ventilated COVID-19 patients sedated with intravenous ketamine (10-20 µg/kg/min) were evaluated at Ali Ibn Abi Talib Hospital, Zahedan, Iran, in 2022 and 2023. The sample size was calculated to detect significant differences with a 95% confidence level. Data collection included demographic information and four sedation scales: Riker Sedation-Agitation Scale, Motor Activity Assessment Scale, Richmond Agitation-Sedation Scale, and Ramsay Sedation Scale. The primary outcome measure was inter-rater reliability, quantified by Cohen's Ka

SUBMITTER: Al-Taie SF 

PROVIDER: S-EPMC12328579 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature