The dissemination potential of Microsporidia MB in Anopheles arabiensis mosquitoes is modulated by temperature.

ABSTRACT: Microsporidia MB, a vertically transmitted endosymbiont of Anopheles mosquitoes, shows strong potential as a malaria control agent due to its ability to inhibit Plasmodium development within the mosquito host. To support its deployment in malaria transmission reduction strategies, it is critical to understand how environmental factors, particularly temperature, influence its infection dynamics. In this study, we investigated the impact of four temperature regimes (22 °C, 27 °C, 32 °C, and 37 °C) on Microsporidia MB prevalence and infection intensity by rearing mosquito larvae under controlled laboratory conditions. Our results demonstrate that elevated temperatures, especially 32 °C, significantly enhance both larval growth and Microsporidia MB infection rates. Population growth modeling f

SUBMITTER: Otieno FG 

PROVIDER: S-EPMC12328603 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature