Top 10 drugs most frequently associated with adverse events of myocarditis and pericarditis.

ABSTRACT: Myocarditis and pericarditis are managed with various treatments, yet prior studies and case reports indicate that certain drug classes may elevate the risk for these inflammatory cardiac conditions. This research aimed to systematically identify the leading drugs most frequently associated with myocarditis and pericarditis cases. Analyses were carried out using the global database of individual case safety reports from 1968 to 2024. We identified the drugs most frequently reported in signal detection with myocarditis and pericarditis, selecting the top 10 drugs based on record count, excluding those used in the treatment of inflammatory cardiac conditions to avoid potential confounding. Two statistical indicators, the information component (IC) with IC₀₂₅ and reporting odds rat

SUBMITTER: Cho J 

PROVIDER: S-EPMC12328665 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature