Impact of magnetic resonance imaging visibility of prostate cancer on partial gland ablation.

ABSTRACT:

Objectives

To evaluate the outcomes of partial gland ablation (PGA) according to prostate cancer (PCa) visibility on magnetic resonance imaging (MRI).

Subjects and methods

Consecutive patients with localized PCa diagnosed by MRI-informed prostate biopsy (PBx), who underwent hemi-gland Cryoablation (CRYO) or hemi-gland High-Intensity Focused Ultrasound (HIFU), were identified from a multicentric database. High-visibility was defined as Prostate Imaging-Reporting and Data System (PIRADS) ≥ 4. The primary endpoint was treatment failure (TF), defined as Grade Group (GG) ≥ 2 on follow-up PBx (FU-PBx), any whole-gland treatment, systemic therapy, metastases or PCa-specific mortality. Kaplan-Meier and Cox regression analyses were performed. Statistically significant if p < 0.05.

SUBMITTER: Kaneko M 

PROVIDER: S-EPMC12328995 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature