Eco-friendly fabrication of ZnO quantum dots using Brassica rapa (L.): metabolomic profiling and antimicrobial efficacy against foodborne pathogens supported by in-silico insights.

ABSTRACT: The growing challenge of drug-resistant pathogens has forced the urgent need for natural and sustainable antimicrobial alternatives. This research explores the green chemistry-based synthesis of zinc oxide quantum dots (ZnO-QDs) employing the ethanolic root extract of Brassica rapa (L.) to assist their formation and stabilization. Characterization of ZnO-QDs confirmed their hexagonal crystalline structure with a nanoscale size (0.8-2.6 nm) and their good stability. GC/MS assay identified β-phenylethyl isothiocyanate and hydroquinone as the main antimicrobial compounds in the essential oil, while LC-ESI-TOF-MS profiling pinpointed the existence of glucosinolates, flavonoids, and phenolic acids as potential active compounds contributing to nanoparticle formation and antimicrobial potential.

SUBMITTER: Alsayed DK 

PROVIDER: S-EPMC12329021 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature