Predicting Progression to Vision-Threatening Complications in Diabetic Retinopathy.

ABSTRACT:

Objective

To characterize the performance of 56 parameters from electroretinography (ERG)/pupillometry, color fundus photography (FP), OCT angiography (OCTA), and ultra-widefield fluorescein angiography (UWF-FA) for predicting which subjects with nonproliferative diabetic retinopathy (NPDR) will progress to vision-threating complications (VTCs) within 48 weeks.

Design

A longitudinal prospective study from 44 trial sites in the United States.

Participants

Subjects had moderate-to-severe NPDR and no center-involved diabetic macular edema. Among the 162 subjects, the mean age was 57 years and 58% were male.

Intervention

Although this study tested an experimental drug, there was no indication of a treatment effect. Results are analyzed over all subjects regardless

SUBMITTER: Davis CQ 

PROVIDER: S-EPMC12329116 | biostudies-literature | 2025 Nov-Dec

REPOSITORIES: biostudies-literature