Interpersonal Physiological Linkage Between People With Behavioral Variant Frontotemporal Dementia and Alzheimer's Disease and Their Informal Caregivers.

ABSTRACT: Physiological linkage, which refers to the degree that people's peripheral physiological responses change in coordinated ways, has been linked to a variety of psychiatric and developmental conditions. In contrast, physiological linkage in neurological conditions has been understudied. Behavioral variant frontotemporal dementia (bvFTD) is characterized by debilitating impairments in socioemotional functioning, including connections with others. We hypothesized that physiological linkage during interactions with loved ones would be reduced in bvFTD. During unrehearsed 10-min discussions of an area of disagreement in 86 dyads (n = 40 bvFTD; n = 35 Alzheimer's disease [AD]; n = 11 healthy controls), we computed dyadic physiological linkage using a composite of six peripheral physiological meas

SUBMITTER: Chen KH 

PROVIDER: S-EPMC12329164 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature