Clinical information prompt-driven retinal fundus image for brain health evaluation.

ABSTRACT:

Background

Brain volume measurement serves as a critical approach for assessing brain health status. Considering the close biological connection between the eyes and brain, this study aims to investigate the feasibility of estimating brain volume through retinal fundus imaging integrated with clinical metadata, and to offer a cost-effective approach for assessing brain health.

Methods

Based on clinical information, retinal fundus images, and neuroimaging data derived from a multicenter, population-based cohort study, the KaiLuan Study, we proposed a cross-modal correlation representation (CMCR) network to elucidate the intricate co-degenerative relationships between the eyes and brain for 755 subjects. Specifically, individual clinical information, which has been followed up

SUBMITTER: Tong N 

PROVIDER: S-EPMC12329875 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature